Welcome to the International Symposium on Polymer Therapeutics to be held in Valencia.A chance for world-renowned scientists to share their recent research and vision for the future of Polymer Therapeutics to attendees in the context of interdisciplinary research at the interface of biology, chemistry, pharmaceutical sciences, and medicine.
A chance for world-renowned scientists to share their recent research and vision for the future of Polymer Therapeutics to attendees in the context of interdisciplinary research at the interface of biology, chemistry, pharmaceutical sciences, and medicine.
Discussion leader: Julen Oyarzabal (Tyris Therapeutics Spain)
12.15 Daniel Siegwart (UT Southwestern Medical Center, USA)
Zwitterionic phospholipidation of cationic polymers facilitates systemic mRNA delivery to the spleen and lymph nodes.
12.45 Satoshi Suchida (Kyoto Prefectural University of Medicine, JP) Polymer Therapeutics for efficient mRNA delivery
13:15 Yao Jin (Ludwig-Maximilians-University Munich, DE) Synthesis and application of spermine-based poly(β-amino Ester)s for siRNA delivery
13.25 Zerong Ma (UNSW Sydney, AUS) Miktoarm star polymer nanoparticles enable siRNA delivery for the treatment of lung cancer
13.35 Stefano Salmaso (Univ Padova, IT) Lipoplex-Mediated Oligonucleotide Delivery: Enhanced Crossing of Cell Barriers
13.40 Gabriela Arias Alpizar (Univ Leiden, NL) Elucidating Nanoparticle Behavior Using Zebrafish
13.45 Anna Scomparin (Univ Turin, IT) Alkylic-Cyclodextrin Cationic Polymers: A Novel siRNA Delivery System for Glioblastoma Therapy
Enjoy our poster exhibition during lunch time.
Discussion Leader: Ronit Satchi-Fainaro (Tel Aviv Univ, IL)
15.15 Susan N. Thomas (Georgia Tech, USA) Polymer drug delivery systems
for immunotherapeutic drug delivery to the lymphatic system
15.45 Lutz Nuhn (Univ Mainz, Germany) Macromolecule-Based Strategies For
Enhancing Immunotherapy Responses By Macrophage Repolarization
16.15 Helena Florindo (Univ Lisbon, PT) Multivalent Anticancer NanoVaccines
16.45 Bárbara Ibarzo Yus (UCL, UK and IBEC, SP) PMPC-PDPA polymersomes in cancer vaccine development
16.55 Liane Moura (iMed. ULisboa, PT) Multivalent branched poly-l-glutamic acid-based nanovaccine sensitizes melanoma to anti-PD1 therapy
17.05 Francesca Mastrotto (Univ Padova, IT) Mannosylated polycations for therapeutic nucleic acid Delivery in cancer vaccination
Enjoy our poster exhibition during lunch time.
An Interactive Session
17.45 – 19:15 Round Table Discussion: Including topics such as identifying Unmet needs: Drug targets and Diseases, Modalities needs – expanded space; Patient’s needs; Needs on Clinical Translation, such as, Characterization techniques and other capabilities or New advances on disruptive polymer sciences.
Marianne B. Ashford (AstraZeneca, UK) and Manuel Sánchez-Félix (Novartis, USA).
Ruth B. Schmid (Sintef, No)
Cameron Alexander (Univ Nottingham, UK)
Discussion Leaders: Andrew Lewis (Quotient Sciences, UK)
9.45 Maria J. Blanco (Univ Navarra, Sp) Nanomedicines for the treatment of
10.15 Mohammed Balogun (CSIR, SouthAfrica) Rational Design of Polymer Conjugates for the treatment of malaria in children
10.45 Gloria García Palacios (Sanofi. France) Overview of EU and FDA Pediatric Regulations
11.15 Tetiana Melnyk (CIPF, SP) A Polyglutamate-Based Intranasal Drug Delivery Platform for Pediatric Glioma Treatment.
Enjoy our poster and Exhibition.
11:45 Paco Fernandez-Trillo (Univ Birmingham, UK)
Delivery of Antimicrobials through Peptide and Responsive Chemistry
11:55 Patrick Weber (ETH Zürich, SW)
Zwitterionic polymer-drug conjugates with lubricating, anti-inflammatory activity for the treatment of osteoarthritis
12:05 Elaine Ferguson (Cardiff Univ, UK)
Dextrin conjugation prevents colistin-induced acute kidney injury in mice
12:15 Tommaso Tedeschini (Univ Pavoda, IT)
Pegylated peptide-cleavable linkers designed to provide stable and active antibody-drug conjugates.
12:25 Silvia Acosta-Gutierrez (UCL, UK)
A Multiscale Study of Phosphorylcoline Driven Cellular Phenotypic Targeting
12:30 Zsuzsa Baranyai (INMA, SP)
Antitubercular Drug Delivery with Polysaccharide-Based Nanocarriers
12:35 Alexander Lamoot (Univ Ghent, BE)
Lipid Nanoparticles encapsulating PolyI:C A Potent Adjuvant for Recombinant Spike S1 SARS-CoV-2 vaccination
12.40 Antonella Grigoletto (Univ Padova, IT)
Stability and in-vivo profile of a new circular site-specific PEGylated G-CSF
Discussion Leaders: Michael Wagner (DE)
12.45 Cristianne Rijcken (Cristal Therapeutics, NL)
Conception till Clinical Translation of Core-Crosslinked (CRIPEC®) Polymeric Micelles and Product Diversification
13.15 Michael Bevilacqua (Amicrobe, USA)
AmicidinsTM: Synthetic Biologics Headed into Clinical Trials in Surgery and Trauma
Enjoy the poster and Exhibition during Lunch time
Session in honor to Prof Hiroshi Maeda. Father of the EPR effect and a Giant in our field
15.00 – 16:45 Round Table Discussion: Fundamentals of EPR and tumor targeting, on novel insights related to transcytosis, hitchhiking and macrophage retention, on practical aspects of dealing with EPR variability, and on how to move “passively targeted” cancer nanomedicines forward both clinically and industrially.
Discussion Leader: Twan Lammers (RWTH Aachen University Clinic, DE)
Milles A. Miller (MGH Center Systems Biology, Harvard Med School, USA)
Khaled Greish (Al-Jawhara Centre, Kingdom of Bahrain)
Warren Chan (Univ Toronto, CA
Discussion Leader: Ana Armiñán (CIPF, SP)
16:45 Fernanda Rodríguez-Otormín (CIPF, SP) A rationally designed polypeptide-based combination conjugate for the treatment of metastatic triple negative breast cancer
16:50 Mariana Bento (iMed Univ Lisboa, PT) Multifunctional Polymeric Nanoplatform to Overcome Pancreatic Cancer Immune Evasion
16:55 Paul Strasser (Johannes Kepler University Linz, Aus) Bottlebrush, High-Molecular-Weight Polyphosphazene-G-Poly (L-Glutamic Acid) As Fully Biodegradable Polymer Therapeutics
17:00 Paz Boix-Montesinos (CIPF, SP) The Development and Characterization of Advanced In Vitro Models for the Evaluation of Polypeptide-Drug Conjugates
17:05 Diana Matias (UCL, UK) Polymersomes With Tunable Avidity to LRP1 In Healthy and Glioma Model
17:10 Carmen Moya-Lopez (Univ Lorraine, FR) Multifunctional PLA/Gelatin Bionanocomposites for Tailored Drug Delivery Systems
17:15 Antoni Serrano (CIPF, SP) Optimization of Preclinically Relevant Three-Dimensional Prostate Cancer Models
Discussion Leaders: Cameron Alexander (Univ Nottingham, UK)
17:45 Adam Gormley (Rutgers Univ , USA)- Discovering Advanced polymeric systems by an Automated and AI-driven polymer chemistry platform.
18.15 Roey Amir (Tel Aviv Univ, IL) Architectural changes as a tool for controlling the stability and reactivity of polymeric assemblies.
18.45 Robert Luxenhofer (Helsinki Univ, FI), and Ann-Christin Pöppler (Univ Würzbug, DE) Taking up the chase with NMR Spectroscopy – From structural
insights into solid drug-polymer formulations to their fate in biorelevant media.
19.15 – Sebastien Rouzeau (Tosoh Biosciences, DE) Polymer therapeutics deserve a better light
* Refreshment will be provided